Peptide Name
Agouti related protein precursor.
Synonym
None
Swiss ID
AGSR_MOUSE
Gene Name
AGRP OR ART OR AGRT.
Comment
FUNCTION: plays a role in weight homeostasis. may play a role in the regulation of melanocortin receptors within the hypothalamus and adrenal gland, and therefore in the central control of feeding.
TISSUE SPECIFICITY: expressed in arcuate nucleus and median eminence, adrenal gland (medulla), hypothalamus, testis, and lung.
INDUCTION: hypothalamic expression is elevated circa 10 fold in ob/ob and db/db mice.
SIMILARITY: belongs to the agouti family
Sequence Comment
1-20
SIGNAL
POTENTIAL.
21-131
CHAIN
AGOUTI RELATED PROTEIN.
86-128
DOMAIN
CYS-RICH.
86-101
DISULFID
BY SIMILARITY.
93-107
DISULFID
BY SIMILARITY.
100-118
DISULFID
BY SIMILARITY.
104-128
DISULFID
BY SIMILARITY.
109-116
DISULFID
BY SIMILARITY.
Length
131AA
Molecular Weight
14432
Species:
Mus musculus (Mouse).
Sequence: 
        1    MLTAMLLSCV LLLALPPTLG VQMGVAPLKG IRRPDQALFP EFPGLSLNGL KKTTADRAEE VLLQKAEALA EVLDPQNRES RSPRRCVRLH ESCLGQQVPC    100
      101    CDPCATCYCR FFNAFCYCRK LGTATNLCSR T