| Peptide Name |
ADM precursor [Contains: Adrenomedullin, Proadrenomedullin N-20 terminal peptide]. |
| Synonym |
AM,Proadrenomedullin N-20 terminal peptide (ProAM-N20,ProAM N-terminal 20 peptide,PAMP, |
| Swiss ID |
ADML_RAT |
| Gene Name |
ADM. |
| Comment |
| FUNCTION: |
am and pamp are potent hypotensive and vasodilatator agents. |
| SUBCELLULAR LOCATION: |
secreted. |
| TISSUE SPECIFICITY: |
expressed in adrenal glands, lung, kidney, heart, spleen, duodenum and submandibular glands. |
| SIMILARITY: |
belongs to the adrenomedullin family |
|
Sequence
Comment |
1-21 |
|
BY SIMILARITY. |
22-41 |
|
PROADRENOMEDULLIN N-20 TERMINAL PEPTIDE. |
45-91 |
|
BY SIMILARITY. |
94-143 |
|
ADRENOMEDULLIN. |
149-185 |
|
PREPROAM C-TERMINAL FRAGMENT (BY SIMILARITY). |
107-112 |
|
BY SIMILARITY. |
41-41 |
|
AMIDATION (G-42 PROVIDE AMIDE GROUP) (BY SIMILARITY). |
143-143 |
|
AMIDATION (G-144 PROVIDE AMIDE GROUP) (BY SIMILARITY). |
|
Length |
185AA |
Molecular
Weight |
20636 |
Species: |
Rattus norvegicus (Rat). |
| Sequence: |
1 MKLVSIALML LGSLAVLGAD TARLDTSSQF RKKWNKWALS RGKRELQASS SYPTGLVDEK TVPTQTLGLQ DKQSTSSTPQ ASTQSTAHIR VKRYRQSMNQ 100
101 GSRSTGCRFG TCTMQKLAHQ IYQFTDKDKD GMAPRNKISP QGYGRRRRRS LPEVLRARTV ESSQEQTHSA PASPAHQDIS RVSRL
|
|
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